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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
26.06
Human Site:
Y599
Identified Species:
38.22
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
Y599
E
L
L
N
Q
N
G
Y
D
E
S
C
D
L
W
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
Y691
E
L
L
N
Q
N
G
Y
D
E
S
C
D
L
W
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
Y851
E
L
L
N
Q
N
G
Y
D
E
S
C
D
L
W
Dog
Lupus familis
XP_547953
806
90703
Y606
E
L
L
N
H
N
G
Y
D
E
S
C
D
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
Y575
T
P
C
F
T
L
Q
Y
A
A
P
E
L
L
A
Rat
Rattus norvegicus
Q63531
735
82865
Q529
T
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
Y516
E
L
L
N
H
N
G
Y
D
E
S
C
D
L
W
Chicken
Gallus gallus
Q5F3L1
789
89022
Y589
E
L
F
N
H
N
G
Y
D
E
S
C
D
L
W
Frog
Xenopus laevis
P10665
733
82620
L534
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
M546
K
P
S
N
I
L
Y
M
D
D
S
G
N
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
P798
A
N
L
V
T
Y
S
P
A
V
D
I
Y
G
L
Honey Bee
Apis mellifera
XP_395099
910
102507
Y618
E
V
I
A
R
Q
G
Y
D
Q
S
C
D
L
W
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Q565
V
L
D
V
G
D
S
Q
P
E
Y
N
E
Q
C
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
E559
R
A
Y
E
Q
D
G
E
Y
D
A
S
C
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
M278
M
D
V
D
G
H
V
M
L
T
D
F
G
L
A
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
C484
Y
Q
G
H
I
A
L
C
D
F
G
L
C
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
93.3
N.A.
13.3
0
N.A.
93.3
86.6
13.3
20
N.A.
6.6
60
13.3
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
93.3
86.6
33.3
40
N.A.
6.6
86.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
7
0
0
13
7
7
0
0
0
13
% A
% Cys:
0
0
7
0
0
0
0
7
0
0
0
44
13
0
7
% C
% Asp:
0
7
7
7
0
13
7
0
57
13
13
0
44
13
7
% D
% Glu:
44
0
7
7
0
0
0
7
0
44
0
7
7
0
0
% E
% Phe:
0
0
7
7
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
7
7
0
13
0
50
0
7
0
7
7
7
7
0
% G
% His:
0
0
0
7
25
13
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
0
13
0
0
0
0
0
0
7
7
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% K
% Leu:
0
44
38
0
7
13
7
7
7
0
0
7
7
63
19
% L
% Met:
7
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
44
0
38
0
0
0
0
0
13
7
0
0
% N
% Pro:
0
13
0
0
0
0
0
7
7
7
7
0
0
7
0
% P
% Gln:
7
7
0
0
25
7
7
13
0
7
0
0
0
7
0
% Q
% Arg:
7
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
19
0
0
0
57
7
0
0
0
% S
% Thr:
13
0
0
0
13
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
13
13
19
0
0
7
0
0
13
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
44
% W
% Tyr:
7
0
7
7
0
7
7
50
7
0
7
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _